Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Nkx2-1  NK2 homeobox 1   (Synonyms: T/EBP, thyroid-specific enhancer-binding protein, thyroid transcription factor-1, tinman, Titf1, Ttf-1)
Results	Reference
1	J:187154 Arora R, Metzger RJ, Papaioannou VE, Multiple roles and interactions of tbx4 and tbx5 in development of the respiratory system. PLoS Genet. 2012 Aug;8(8):e1002866
1	J:249800 Burnett JB, Lupu FI, Eggenschwiler JT, Proper ciliary assembly is critical for restricting Hedgehog signaling during early eye development in mice. Dev Biol. 2017 Oct 1;430(1):32-40
1	J:85554 del Barco Barrantes I, Davidson G, Grone HJ, Westphal H, Niehrs C, Dkk1 and noggin cooperate in mammalian head induction. Genes Dev. 2003 Sep 15;17(18):2239-44
1*	J:93148 Desai TJ, Malpel S, Flentke GR, Smith SM, Cardoso WV, Retinoic acid selectively regulates Fgf10 expression and maintains cell identity in the prospective lung field of the developing foregut. Dev Biol. 2004 Sep 15;273(2):402-15
1	J:153236 Harris-Johnson KS, Domyan ET, Vezina CM, Sun X, beta-Catenin promotes respiratory progenitor identity in mouse foregut. Proc Natl Acad Sci U S A. 2009 Sep 22;106(38):16287-92
1	J:276709 Hashimoto K, Yamaguchi Y, Kishi Y, Kikko Y, Takasaki K, Maeda Y, Matsumoto Y, Oka M, Miura M, Ohata S, Katada T, Kontani K, Loss of the small GTPase Arl8b results in abnormal development of the roof plate in mouse embryos. Genes Cells. 2019 Jun;24(6):436-448
1	J:130851 Lavado A, Lagutin OV, Oliver G, Six3 inactivation causes progressive caudalization and aberrant patterning of the mammalian diencephalon. Development. 2008 Feb;135(3):441-50
1	J:62027 Martinez Barbera JP, Clements M, Thomas P, Rodriguez T, Meloy D, Kioussis D, Beddington RS, The homeobox gene Hex is required in definitive endodermal tissues for normal forebrain, liver and thyroid formation. Development. 2000 Jun;127(11):2433-45
1	J:193395 Mukhopadhyay S, Wen X, Ratti N, Loktev A, Rangell L, Scales SJ, Jackson PK, The ciliary G-protein-coupled receptor Gpr161 negatively regulates the Sonic hedgehog pathway via cAMP signaling. Cell. 2013 Jan 17;152(1-2):210-23
1	J:283357 Nowotschin S, Setty M, Kuo YY, Liu V, Garg V, Sharma R, Simon CS, Saiz N, Gardner R, Boutet SC, Church DM, Hoodless PA, Hadjantonakis AK, Pe'er D, The emergent landscape of the mouse gut endoderm at single-cell resolution. Nature. 2019 May;569(7756):361-367
1	J:104523 Ribes V, Wang Z, Dolle P, Niederreither K, Retinaldehyde dehydrogenase 2 (RALDH2)-mediated retinoic acid synthesis regulates early mouse embryonic forebrain development by controlling FGF and sonic hedgehog signaling. Development. 2006 Jan;133(2):351-61
1*	J:31212 Shimamura K, Hartigan DJ, Martinez S, Puelles L, Rubenstein JL, Longitudinal organization of the anterior neural plate and neural tube. Development. 1995 Dec;121(12):3923-33
1	J:138862 Warr N, Powles-Glover N, Chappell A, Robson J, Norris D, Arkell RM, Zic2-associated holoprosencephaly is caused by a transient defect in the organizer region during gastrulation. Hum Mol Genet. 2008 Oct 1;17(19):2986-96
1	J:87046 Zoltewicz JS, Stewart NJ, Leung R, Peterson AS, Atrophin 2 recruits histone deacetylase and is required for the function of multiple signaling centers during mouse embryogenesis. Development. 2004 Jan;131(1):3-14